鲍官虎

日期：2017.11.14来源：暂无点击数：27

安徽农业大学教授，博士生导师。

1996年毕业于安徽农业大学经济林专业，1999年6月在中国药科大学获硕士学位，2002.8在中国科学院上海药物研究所获博士学位。2002.7-2004.7 上海药物研究所天然药物化学研究室，助理研究员，期间到诺华公司瑞士总部三个月博士后。2004.7-2008.7 先后在美国亚利桑那州立大学癌症研究所, 亚利桑那大学西南天然产物研究中心，哥伦比亚大学医学院, 从事天然产物化学作博士后工作。2008.8哥伦比亚大学医学院Associate Research Scientist

we are hiring: Post doc position in Natural Products Chemistry, chemical biology, Neuropharmacology，20,000－30,000$/year+benefits
call: 86-551-65786165，or email: baoguanhu@ahau.edu.cn
http://tealab.ahau.edu.cn/tzgg/67822.htm

　主讲课程：

Scientific Writing (in English)

天然产物化学开发与利用,天然药物研究进展

2011年3月开始学校天然产物开发和利用教学

科研领域

天然产物化学，植物化学，中草药化学，天然药物研究与开发，蛋白质纯化，蛋白质复合物的制备及其在癌症，肾损伤等疾病方面的功能研究

科研情况：

主要研究领域：

天然产物化学，植物化学，中草药化学，天然药物研究与开发，蛋白质纯化，蛋白质复合物的制备及其在癌症，肾损伤等疾病方面的功能研究

　代表性文章：

1. Guan-Hu Bao*, Chi-Tang Ho, Jonathan Barasch, The Ligands of Neutrophil Gelatinase-Associated Lipocalin RSC Advances, 2015, 5, 104363-104374

2. Guan-Hu Bao*, Jonathan Barasch, Jie Xu, Wei Wang, Feng-Lin Hu, Shi-Xian Deng. Purification and structural characterization of “simple catechol”, the NGAL-Siderochelin siderophore in human urine RSC Advances 2015, 5, 28527-28535

3. Wen-Jun Zheng, Xiao-Chun Wan, Guan-Hu Bao*. Brick dark tea: a review of the manufacture, chemical constituents,and bioconversion of the major chemical components during fermentation. Phytochemistry Reviews 2015,14(3), 499-523

4. Jie Xu, Feng-Lin Hu, Wei Wang, Xiao-Chun Wan, Guan-Hu Bao*, Investigation on biochemical compositional changes during the microbial fermentation process of Fu brick tea by LC-MS based metabolomics, Food Chemistry,2015, 186, 176-184

5 Yun-Fei Zhu, Jing-Jing Chen, Xiao-Ming Ji, Xin Hu, Tie-Jun Ling, Zheng-Zhu Zhang, Guan-Hu Bao*, Xiao-Chun Wan. Changes of major tea polyphenols and production of four new B-ring fission metabolites of catechins from post-fermented Jing-Wei Fu brick tea. Food Chemistry, 2015, 170, 110-117
6 Yue, Y., Chu, G.X., Liu, X.S., Tang, X., Wang, W., Liu, G.J., Yang, T., Ling, T.J., Wang, X.G, Zhang, Z.Z., Xia, T., Wan, X.C, Bao, G.H.* (2014). TMDB: A literature-curated database for small molecular compounds found from tea. BMC Plant Biology, 2014,14, 243

7 Ruili Lu, Xiaoxiao Liu, Sha Gao, Wancun Zhang, Fan Peng, Fenglin Hu*, Bo Huang, Longyun Chen, Guan-Hu Bao*, Chunru Li, Zengzhi Li. New tyrosinase inhibitors from Paecilomyces gunnii. J. Agric. Food Chem 2014, 62(49), 11917-23.

8 Lu, R.L.; Hu, F.L.; Bao, G.H.* A New Fatty acid from the Leaves and Stems of Clerodendron trichotomum. Chem. Nat. Compd. 514.12 2013, 2014, 50(1), 65-67.

9 李丽，鲍官虎. 冻绿茎部化学成分的研究. 天然产物研究与开发. 2013, 25（11）, 1519-1521

10 Bao, G.H. *; Xu, J.; Hu, F.L.; Wan X.C.; Deng, S.X.; Barasch J. EGCG inhibit chemical reactivity of iron through forming an Ngal-EGCG-iron complex. BioMetals, 2013, 26(6),1041-1050.

11 Lu, R.L.; Luo, F.F.; Hu, F.L.*; Huang, B.; Li, C.R.; Bao, G.H.* Identification and production of a novel natural pigment, Cordycepoid A, from Cordyceps bifusispora Appl. Microbiol. Biotechnol. 2013, 97(14), 6241-6249.

12 Dong, X.J.; Zhu, Y.F.; Bao, G.H. *; Hu, F.L.; Qin, G.W. New Limonoids and a Dihydrobenzofuran Norlignan from the Roots of Toona sinensis. Molecules 2013, 18(3), 2840-2850.

13 George R. Pettit, Rui Tan, Guan-Hu Bao, Noeleen Melody, Dennis L. Doubek, Song Gao, Jean-Charles Chapuis, and Lee Williams, Antineoplastic Agents. 587. Isolation and Structure of 3-Epipancratistatin from Narcissus cv. Ice Follies，Journal of Natural Products, 2012, 75 (4), 771-773

14 Bao, Guanhu; Clifton, Matthew; Hoette, Trisha M; et al. Iron Traffics in Circulation Bound to Siderocalin (Ngal) in Complex with a Bacterial Metabolite Called Catechol, Nature Chemical Biology, 2010; 6(8), 602-609

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