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谢忠稳

日期:2017.11.14来源:暂无 点击数:54

谢中稳,安徽农业大学全职特聘教授。皖江学者,博士,博士生导师。主要研究领域:茶叶的有效成份对心血管系统保护的分子机制茶叶多酚类化合物对糖和脂代謝调控的分子机制茶叶的有效成份对生物鐘系统调控的分子机制。1999年获中国科学院植物研究所植物学专业博士学位。20007月至2003 7月在University of Kentucky, Graduate Center for Toxicology从事博士后研究;20037月至201212月在University of Kentucky, Graduate Center for Nutritional Sciences从事研究,任研究科学家和资深研究科学家。先后参与国家自然科学基金重大项目和美国NIH R01项目的研究。在Journal of Clinical Investigation (IF:13.765); Nucleic Acids Research (IF:8.808) J Biol Chem (IF4.651)Arteriosclerosis, Thrombosis, and Vascular Biology (IF6.338)Cardiovascular research (IF5.94) Am J Physiol –Heart and C (IF3.629)等国际知名杂志发表论文30多篇,总计被引次数近千次,H因子16

 主讲课程

分子营养学;营养与健康;茶与健康

发表的主要论文:

 1.      Xie Z., Su W., Liu S., Zhao G., Esser K., Schroder E., Lefta M., Stauss H., Guo Z. and Gong MC. 2015, Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation. Journal of Clinic Investigation. 125(1),324-3336. (SCI,影响因子13.765)

2.      Huang J., Wang Y., Xie Z., Zhou Y. and Wan X. 2014,The anti-obesity effects of green tea in human intervention and basic molecular studies. European Journal of Clinic Nutrition 68, 1075-1087(SCI,影响因子2.95)

3.      Jiang L., Li W., Wang Y., Zhang X, Yu D., Yin Y., Xie Z. and Yuan Y. 2014, Effects of Cichoric Acid Extract from Echinacea purpurea on Collagen-induced Arthritis in Rats. The American J of Chinese Medicine 42(3): 679-692 (SCI,影响因子2.625)

4.      Huang J., Zhang Y., Zhou Y., Zhang Z., Xie Z., Zhang J and Wan X. 2013, Green Tea Polyphenols Alleviate Obesity in Broiler Chickens through the Regulation of Lipid-Metabolism-Related Genes and Transcription Factor Expression. Journal of Agricultural. Food Chemistry., 61 (36), 8565–8572 (SCI,影响因子3.107)

5.      Yu D., Yuan Y., Jiang L.,Tai Y., Yang X., Hu F. and Xie Z. 2013, Anti-inflammatory effects of essential oil in Echinacea purpurea L. Pak. J. Pharm. Sci., Vol.26, No.2, 403-408 (SCI,影响因子1.103)

6.      Liu S., Xie Z., Daugherty, A., Cassis L., Pwarson K., Gong MC. and Guo Z.. 2013, Mineralocorticoid Receptor Agonists Induce Mouse Aortic Aneurysm Formation and Rupture in the Presence of High Salt. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1568-1579 (SCI,影响因子6.338)

7.      Su W, Xie Z, (co-first authors), Liu S, Calderon LE, Guo Z, Gong MC. 2013, Smooth muscle-selective CPI-17 expression increases vascular smooth muscle contraction and blood pressure. American Journal of Physiology-Heart and Circulatory Physiology 305(1): H104-13 (SCI,影响因子4.23)

8.      Kuang L., Kou H., Xie Z., Zhou Y., Feng X., Wang L. and Wang Z. 2013, A Non-catalytic Function of Rev1 in Translation DNA Synthesis and Mutagenesis is Mediated by Its Stable Interaction with Rad5. DNA Repair 12(1):27-37 (SCI,影响因子4.274)

9.      Liu S., Xie Z., Zhao Q. (co-first authors), Pang H., Turk J., Calderon L., Su W., Zhao G., Xu H., Gong MC and Guo Z.. 2012, Smooth Muscle-Specific Expression of iPLA β Participates in the Initiation and Early Progression of Vascular Inflammation and Neointima Formation. Journal of Biological Chemistry. 287 (29):24739-24753 (SCI,影响因子4.651)

10.  Calderon L., Liu S., Su W., Xie Z., Guo Z., Eberhard W. and Gong MC.2012, iPLA2β over-expression in smooth muscle exacerbates Angiotensin II-induced hypertension and vascular remodeling. PLOS ONE 7(2): e31850 (SCI,影响因子3.73)

11.  Su W., Xie Z., (co-first authors), Guo Z., Duncan M., Lutshumba J., Gong MC,

   2012 Altered clock gene expression and vascular smooth muscle diurnal contractile

    variation in type 2 diabetic db/db mice. American Journal of Physiology-Heart

     and Circulatory Physiology 302(3): H621-33SCI,影响因子4.23)

12.  Xie Z., Liu D., Liu S., Turk J., Guo, Z. 2011. Identification of a cAMP-response element in RGS2 promoter as a Key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in VSMC. Journal of Biological Chemistry. 286 (52), 44646-44658 (SCI,影响因子4.651)

13.  Xie Z., Gong MC., Su W., Xie DP., Turk J. and Guo Z. 2010, Group VIA phospholipase A2 beta participates in high glucose induced activation of RhoA/ROCK and PKC/CPI-17 pathway in vascular smooth muscle cells and in herper-contractivity of diabetic animals. Journal of Biological Chemistry 285(12) : 8628-37SCI,影响因子4.651

14.  Xie Z., Gong MC., Su W., Turk J. and Guo Z. 2007, Group VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells. Journal of Biological Chemistry 282(35):25278-89SCI,影响因子4.651

15.  Xie Z., Su W., Guo Z., Pang H., Post SR. and Gong, MC. 2006, Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells. Cardiovascular Research 69(2):491-501SCI,影响因子5.94

16.  Pang H., Guo Z., Xie Z., Su W. and Gong, MC. 2006, Divergent kinase signing mediates agonist-induced phosphorylation of phosphatase inhibitory proteins PHI and CPI-17 in vascular smooth muscle cells. American Journal of Physiology-cell physiology 290(3):C892-9SCI,影响因子3.67

17.  Xie Z., Zhang Y., Guliaev AB., Shen H., Huang B., Singer B., and Wang Z. 2005, The p-benzoquinone DNA adducts derived from benzene are highly mutagenic. DNA Repair 4(12):1399-409SCI,影响因子4.274

18.  Pang H., Guo Z., Su W., Xie Z., Eto M., Gong MC. 2005, RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells. American Journal of Physiology-Cell Physiology 289 (2):C352-360SCI,影响因子3.67

19.  Xie Z., Liu S., Zhang Y., and Wang Z. 2004, Roles of Rad23 protein in yeast nucleotide excision repair. Nucleic Acids Research 32 (20): 5981-90SCI,影响因子8.808

20.  Zhao B., Xie Z., (co-first authors), Shen H., and Wang Z., 2004. Role of DNA polymerase h in the bypass of abasic sites in yeast cells. Nucleic Acids Research 32 (13): 3984-94SCI,影响因子8.808

21.  Guo D., Xie Z., Shen H., and Wang Z. 2004. A non-catalytic function of Rev1 in response to acetylaminofluorene-dG DNA adducts in yeast: stimulating Polz-catalyzed translesion synthesis.  Nucleic Acids Research 32 (3): 1122-30 SCI,影响因子8.808

22.  Xie Z., Braithwaite E., Guo D., Geacintov N., and Wang Z. 2003. Mutagenesis of Benzoapyrene diolepoxide in yeast: requirement for DNA polymerase z and involvement of DNA polymerase h. Biochemistry 42(38): 11253-62 (SCI,影响因子3.194

23.   Zhou H., Xie Z., Ge S. 2003. Microsatellite analysis of genetic diversity and    population genetic structure of wild rice (Oryza rufipogon) in China. Theoretical and Applied Genetics 107 (2): 332-39SCI,影响因子3.507

24.  Zhang Y., Wu X., Yuan F., Xie Z., and Wang Z. 2001. Highly frequent frame-  

shift DNA synthesis by human DNA polymerase m. Molecular and Cellular

    Biology 21(23): 7995-8006SCI,影响因子5.036

25.  Xie Z., Lu Y., Ge S., Hong D., and Li F. 2001. Clonality in wild rice (Oryza. rufipogon) and its implication for conservation managements. American Journal of Botany 88:1058-68SCI,影响因子2.586

26.  Xie Z., Ge S., and Hong D., 1999. Preparation of DNA from silica gel dried mini-amount of leaves of Oryza rufipogon for RAPD studies and total DNA bank construction. Acta Botanica Sinica 41 (8): 807-812SCI,影响因子3.448

27.  Qian, W., Xie, Z., Ge S., and Hong D. (2001) Distribution and conservation of an endangered wild rice Oryza granulata in China, Acta Botania Sinica, 43(12): 1279-1287 (SCI,影响因子3.448


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